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ED4S

Ethylenediaminetetraacetic acid tetrasodium salt hydrate

practical grade, ≥95%

Synonym(s):

EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate

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About This Item

Linear Formula:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O
CAS Number:
Molecular Weight:
380.17 (anhydrous basis)
UNSPSC Code:
12352116
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:
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grade

practical grade

Quality Segment

assay

≥95%

form

powder

reaction suitability

reagent type: chelator

solubility

soluble, clear, colorless (32g plus 200ml of water)

InChI

1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4

InChI key

GXFFSKMBMYHTAE-UHFFFAOYSA-J

Application

EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.
Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

Preparation Note

Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

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036990369903701
grade

practical grade

grade

reagent grade

grade

reagent grade

grade

-

assay

≥95%

assay

≥99.0% (KT)

assay

≥99.0% (KT)

assay

≥97.0% (KT)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

solubility

soluble, clear, colorless (32g plus 200ml of water)

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

-

reaction suitability

reagent type: chelator

reaction suitability

reagent type: chelator

reaction suitability

reagent type: chelator

reaction suitability

-

grade

practical grade

grade

reagent grade

grade

reagent grade

grade

-

assay

≥95%

assay

≥99.0% (KT)

assay

≥99.0% (KT)

assay

≥97.0% (KT)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

solubility

soluble, clear, colorless (32g plus 200ml of water)

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

-

reaction suitability

reagent type: chelator

reaction suitability

reagent type: chelator

reaction suitability

reagent type: chelator

reaction suitability

-


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signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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