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Merck

SNX6

sorting nexin 6

Synonyms:
MSTP010, TFAF2
Species:
UniProtKB ID:
Gene ID:
  • Human(58533) Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(72183) sorting nexin 6
  • Rat(362738) sorting nexin 6
  • naked mole-rat(101716031) sorting nexin 6
  • domestic guinea pig(100729652) sorting nexin 6
  • sheep(101118137) sorting nexin 6
  • domestic cat(101082830) sorting nexin 6
  • chicken(771038) sorting nexin 6
  • dog(490648) sorting nexin 6
  • cow(532685) sorting nexin 6
  • fruit fly(34126) CG8282 gene product from transcript CG8282-RA
  • Zebrafish(567182) sorting nexin 6

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SNX6 antibody produced in mouse, clone 3B11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-SNX6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SNX6 (N-term) antibody produced in rabbit, Ig fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-SNX6 antibody produced in mouse, clone SNX6-76, ascites fluid, buffered aqueous solution,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Snx6,
Species
mouse
MISSION® esiRNA, targeting human SNX6,
Species
human