SLC6A4
solute carrier family 6 (neurotransmitter transporter), member 4
Synonyms:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
Species:
Human SLC6A4 (6532), Mouse Slc6a4 (15567), Rat Slc6a4 (25553), domestic guinea pig Slc6a4 (100135619), naked mole-rat Slc6a4 (101705584), Domestic Rabbit SLC6A4 (100340600), Domestic Rabbit SLC6A4 (100351801), dog SLC6A4 (491184), domestic cat SLC6A4 (101091163), Horse SLC6A4 (100053721) ...More
UniProtKB ID:
Gene ID:
- Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
- Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
- domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SLC6A4 antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-SLC6A4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-SLC6A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
flow cytometry
immunofluorescence
flow cytometry
immunofluorescence
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
Species Reactivity
mouse, rat
Application
Small Molecule - Inhibitor
Product Number
Description
Species
Sertraline for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Sertraline for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Ligand
Product Number
Description
Species
esiRNA
Product Number
Description
Species