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Merck

PSMB9

proteasome (prosome, macropain) subunit, beta type, 9

Synonyms:
LMP2, PSMB6i, RING12, beta1i
Species:
UniProtKB ID:
Gene ID:
  • Human(5698) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar 2010]
  • Mouse(16912) proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
  • Rat(24967) proteasome (prosome, macropain) subunit, beta type, 9
  • cow(510593) proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
  • naked mole-rat(101701705) proteasome (prosome, macropain) subunit, beta type, 9
  • domestic guinea pig(100734835) proteasome (prosome, macropain) subunit, beta type, 9
  • domestic cat(101083848) proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
  • sheep(101115834) proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
  • dog(474867) proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PSMB9 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
Anti-PSMB9/LMP2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-PSMB9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PSMB9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence