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Merck

PHOX2A

paired-like homeobox 2a

Synonyms:
ARIX, CFEOM2, FEOM2, NCAM2, PMX2A
Species:
UniProtKB ID:
Gene ID:
  • Human(401) Summary: The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]
  • Mouse(11859) paired-like homeobox 2a
  • Rat(116648) paired-like homeobox 2a
  • naked mole-rat(101698435) paired-like homeobox 2a
  • Zebrafish(404602) paired-like homeobox 2a
  • chicken(395595) paired-like homeobox 2a
  • dog(485208) paired-like homeobox 2a
  • domestic cat(101095370) paired-like homeobox 2a
  • sheep(101103348) paired-like homeobox 2a
  • cow(507670) paired-like homeobox 2a
  • domestic guinea pig(100732349) paired-like homeobox 2a

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PHOX2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-PHOX2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-PHOX2A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-PHOX2A antibody produced in mouse, clone 4F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-PHOX2A Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Phox2a,
Species
mouse