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Merck

HTR7

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled

Synonyms:
5-HT7
Species:
UniProtKB ID:
Gene ID:
  • Human(3363) Summary: The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
  • Mouse(15566) 5-hydroxytryptamine (serotonin) receptor 7
  • Rat(65032) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • Domestic Rabbit(100009356) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • sheep(101122994) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • dog(477762) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • Horse(100009688) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • naked mole-rat(101719078) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • domestic cat(101092146) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • cow(538510) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • chicken(423794) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • domestic guinea pig(100135549) 5-hydroxytryptamine (serotonin) receptor 7

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Small Molecule - Agonist

Product Number
Description
Species
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Species
human, rat
(+)-Fenfluramine hydrochloride, ,
Species
human
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
SB-269970 hydrochloride, powder, ≥98% (HPLC),
Species
human
5-Methoxytryptamine, 97%,
Species
rat, human
1-(2-Methoxyphenyl)piperazine, 98%,
Species
mouse, rat
Ritanserin, powder,
Species
rat, human
Loxapine succinate salt, solid,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HTR7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-HTR7 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-HTR7 (AB3) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, dog, guinea pig, hamster, horse, human, monkey, mouse, pig, rat
Application
ELISA
immunohistochemistry
Anti-HTR7 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
Anti-HTR7 (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Pimozide, ,
Species
human, mouse, rat
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human
Zimelidine dihydrochloride, solid,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Pimozide, ,
Species
human, mouse, rat
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
Fluvoxamine maleate, solid,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human

Proteins

Product Number
Description
Species
5-HT7 Serotonin Receptor from rat, recombinant, expressed in HEK 293 cells,
Species
rat
ChemiSCREEN Membrane Preparation Recombinant Human 5-HT₇ Serotonin Receptor, Human 5-HT7 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HTR7,
Species
human