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Merck

F5

coagulation factor V (proaccelerin, labile factor)

Synonyms:
FVL, PCCF, RPRGL1, THPH2
Species:
UniProtKB ID:
Gene ID:
  • Human(2153) Summary: This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]
  • Mouse(14067) coagulation factor V
  • Rat(304929) coagulation factor V (proaccelerin, labile factor)
  • naked mole-rat(101703568) coagulation factor V (proaccelerin, labile factor)
  • domestic guinea pig(100715882) coagulation factor V (proaccelerin, labile factor)
  • sheep(101123649) coagulation factor V (proaccelerin, labile factor)
  • cow(280687) coagulation factor V (proaccelerin, labile factor)
  • Horse(100058503) coagulation factor V (proaccelerin, labile factor)
  • domestic cat(101085264) coagulation factor V (proaccelerin, labile factor)
  • dog(100685858) coagulation factor V (proaccelerin, labile factor)
  • chicken(374052) coagulation factor V (proaccelerin, labile factor)
  • Zebrafish(327320) coagulation factor V

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-F5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-Factor V antibody produced in mouse, clone HV-1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
dot blot

neutralization

Proteins

Product Number
Description
Species
Factor V human, aqueous glycerol solution, ≥25 units/mg protein,
Species
human
Factor Va human, ≥1500 units/mg protein,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse F5,
Species
mouse
MISSION® esiRNA, targeting human F5,
Species
human