DPH5
diphthamide biosynthesis 5
Synonyms:
CGI-30, HSPC143, NPD015
Species:
Human DPH5 (51611), Mouse Dph5 (69740), Rat Dph5 (295394), fruit fly Dph5 (42663), domestic guinea pig Dph5 (100732624), naked mole-rat Dph5 (101696986), Zebrafish dph5 (100003898), chicken DPH5 (424463), cow DPH5 (508904), sheep DPH5 (101115329) ...More
UniProtKB ID:
Gene ID:
- Human(51611) Summary: This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(69740) DPH5 homolog (S. cerevisiae)
- Rat(295394) diphthamide biosynthesis 5
- fruit fly(42663) Diphthamide methyltransferase
- domestic guinea pig(100732624) diphthamide biosynthesis 5
- naked mole-rat(101696986) diphthamide biosynthesis 5
- Zebrafish(100003898) DPH5 homolog (S. cerevisiae)
- chicken(424463) DPH5 homolog (S. cerevisiae)
- cow(508904) DPH5 homolog (S. cerevisiae)
- sheep(101115329) DPH5 homolog (S. cerevisiae)
- Zebrafish(492514) DPH5 homolog (S. cerevisiae)
- dog(612092) DPH5 homolog (S. cerevisiae)
- domestic cat(101090957) DPH5 homolog (S. cerevisiae)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DPH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-DPH5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-DPH5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence