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Merck

ADORA3

adenosine A3 receptor

Synonyms:
A3AR, AD026, bA552M11.5
Species:
UniProtKB ID:
Gene ID:
  • Human(140) Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11542) adenosine A3 receptor
  • Rat(25370) adenosine A3 receptor
  • dog(403805) adenosine A3 receptor
  • Domestic Rabbit(100008725) adenosine A3 receptor
  • sheep(443330) adenosine A3 receptor
  • cow(780806) adenosine A3 receptor
  • naked mole-rat(101697269) adenosine A3 receptor
  • chicken(373956) adenosine A3 receptor
  • domestic cat(101094689) adenosine A3 receptor
  • domestic guinea pig(100725432) adenosine A3 receptor

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Species
human
AB-MECA, solid,
Species
human, rat
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Adenosine, ,
Species
human
Adenosine, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
VUF 5574, ,
Species
human
3-Deazaadenosine, ,
Species
rat
Tyramine hydrochloride, ≥98%,
Species
human
(S)-(−)-Bay K8644, ≥98% (HPLC), solid,
Species
human, rat
2-Iodoadenosine, 97%,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADORA3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168), Chemicon®, from rabbit,
Species Reactivity
rat
Application
ELISA
immunocytochemistry

western blot
Monoclonal Anti-ADORA3 antibody produced in mouse, clone 1A3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Small Molecule - Inhibitor

Product Number
Description
Species
EHNA hydrochloride, ≥98% (HPLC),
Species
human
Dilazep dihydrochloride, powder,
Species
human
Galangin, autophagy inducing flavonoid,
Species
human, rat
5′-Deoxy-5′-(methylthio)adenosine, ,
Species
human, rat, mouse
S-(4-Nitrobenzyl)-6-thioinosine, ≥98%, solid,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
2-Chloro-2′-deoxyadenosine, antileukemic,
Species
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Species
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Species
human, rat
Adenosine, ≥99%,
Species
human, rat
Theophylline, anhydrous, ≥99%, powder,
Species
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
2-Iodoadenosine, 97%,
Species
human, rat
2-Fluoroadenosine, 97%,
Species
rat, human
2-Fluoroadenine-9-β-D-arabinofuranoside, DNA synthesis and methylation inhibitor,
Species
rat, human
2-Chloroadenosine, ,
Species
human, rat
Chloro-IB-MECA, solid, ≥98% (HPLC),
Species
human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADORA3,
Species
human
MISSION® esiRNA, targeting human TMIGD3,
Species
human