- Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation.
Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation.
Scientific reports (2017-07-14)
Teruhisa Takagishi, Masaya Takehara, Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masahiro Nagahama
PMID28701754
ABSTRACT
Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis. In this study, we treated bone marrow cells (BMCs) from mice with purified α-toxin and found that TER119
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5(6)-Carboxyfluorescein N-hydroxysuccinimide ester, BioReagent, suitable for fluorescence, mixture of isomers, ≥80% (HPLC)