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306576

Sigma-Aldrich

Sodium hydroxide

pellets, semiconductor grade, 99.99% trace metals basis

Synonym(s):

‘Caustic soda’

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About This Item

Linear Formula:
NaOH
CAS Number:
Molecular Weight:
40.00
EC Number:
MDL number:
UNSPSC Code:
12352316
PubChem Substance ID:
NACRES:
NA.21

grade

semiconductor grade

Quality Level

vapor density

>1 (vs air)

vapor pressure

<18 mmHg ( 20 °C)
3 mmHg ( 37 °C)

Assay

99.99% trace metals basis

form

pellets

technique(s)

HPLC: suitable

impurities

<1% Na2CO3

mp

318 °C (lit.)

solubility

water: soluble 1,260 g/L at 20 °C

density

2.13 g/cm3 at 20 °C

SMILES string

[OH-].[Na+]

InChI

1S/Na.H2O/h;1H2/q+1;/p-1

InChI key

HEMHJVSKTPXQMS-UHFFFAOYSA-M

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General description

Sodium hydroxide (caustic soda, NaOH) is a water-soluble inorganic base with a wide range of industrial applications such as titration methods, dissolution testing, and pH adjusting. It is also used as a precipitant to precipitate transition metal hydroxides.

Application


  • Alkaliptosis induction counteracts paclitaxel-resistant ovarian cancer cells: Utilizing sodium hydroxide in ATP6V0D1-mediated ABCB1 inhibition reveals a novel approach to overcoming drug resistance in ovarian cancer, promoting cell death through alkaliptosis. This could significantly impact cancer treatment strategies (Chen et al., 2024).

  • Ozone-activated lignocellulose films blended with chitosan: Research shows potential for creating biodegradable, edible films using sodium hydroxide in the activation process. This application is particularly relevant in food packaging and could revolutionize how we approach sustainable material science (Ebrahimi et al., 2024).

  • Stabilizing fish oil emulsions with tilapia head gelatins: Investigating the effects of sodium hydroxide in the extraction of gelatins, this study highlights its utility in enhancing the stability and usability of fish oil emulsions in food science (Li et al., 2024).

  • Cellulose dissolution in ZnO/NaOH/Water solvent solution: Molecular dynamics simulation studies illustrate how sodium hydroxide aids in dissolving cellulose, with temperature-dependent effects providing insights into polymer science applications, especially in textile and material production (Bourassi et al., 2024).

  • Recycling Metakaolin/Slag-Based Geopolymer Concrete: Sodium hydroxide plays a crucial role in developing geopolymer concretes capable of withstanding severe freeze-thaw conditions, suggesting significant applications in sustainable construction materials (Liu et al., 2024).

Sodium hydroxide is used as a reagent:

  • for the preparation of synthesis solution during the formation of LTA zeolite crystals in the hydrothermal synthesis process.
  • in the synthesis of 2-line ferrihydrite (spHm) and rhombohedral Hm (rhHm) and as a base to adjust the pH of the mixed solution.
  • to raise the pH of the HEPES buffer during catalytic reactivity to nanoparticle (CRNP) assay and synthesis.
  • in the synthesis of zinc oxide nanoparticles from zinc chloride during lithium doping impact on the cathodoluminescence of the nanoparticles.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zeolite LTA/carbon membranes for air separation
Sonia D D, et al.
Microporous and Mesoporous Materials : The Official Journal of the International Zeolite Association, 115, 51-60 (2008)
Dry powder assay rapidly detects metallic nanoparticles in water by measuring surface catalytic reactivity.
Xiangyu B, et al.
Environmental Science & Technology, 52, 13289-13297 (2018)
Crystal dissolution by particle detachment
Guomin Z, et al.
Nature Communications, 14, 6300-6300 (2023)
Chemoselective, solvent-free aldol condensation reaction.
Raston CL and Scott JL.
Green Chemistry, 22(2), 49-52 (2000)
Effects of lithium doping and post-processing on the cathodoluminescence of zinc oxide nanoparticles
K M, et al.
Microscopy and Microanalysis, 12, 1510-1511 (2006)

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