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LiChrospher® 100 RP-18 endcapped (5 µm) HPLC Columns

HPLC sorbent

Synonym(s):

TM=["LiChrospher"] C18 sorbent for HPLC

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About This Item

UNSPSC Code:
41115709
NACRES:
SB.52

product name

LiChrospher® 100 RP-18 endcapped (5 µm),

material

stainless steel column

Agency

suitable for USP L1

product line

LiChrospher®

feature

endcapped

packaging

1 ea of

extent of labeling

21.6% Carbon loading

parameter

60 °C max. temp.

technique(s)

HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)

surface area

350 m2/g

matrix

fully porous particle

matrix active group

C18 bonding phase

particle size

5 μm

pore size

100 Å pore size

operating pH range

2-7.5

bulk density

200‑400 kg/m3

separation technique

reversed phase

storage temp.

no temp limit

General description

LiChrospher® RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carrier with revered phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.

Application


  • Simultaneous quantification of delta-9-THC, THC-acid A, CBN and CBD in seized drugs using HPLC-DAD: The robustness of the LiChrospher® 60 RP-select B column is highlighted in forensic science, where it is used to accurately identify and quantify cannabinoids, demonstrating its critical role in legal and forensic analyses (Ambach et al., 2014).

  • RP-HPLC separation and characterization of unknown impurities of a novel HIV-protease inhibitor Darunavir by ESI-MS and 2D NMR spectroscopy: The LiChrospher® 60 RP-select B column′s exceptional selectivity and performance are utilized to identify novel impurities in Darunavir, highlighting its application in developing more effective HIV treatments (Nageswara Rao et al., 2013).

  • Quantification of pralidoxime (2-PAM) in urine by ion pair chromatography-diode array detection: Demonstrating versatility, this column was used to detect therapeutic agents in clinical settings, supporting treatment regimes for poisonings where rapid and accurate drug monitoring is essential (John et al., 2012).


Analysis Note

Application test: passes test
Pressure: ≤ 50 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
stability testing (performance): passes test
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm

Legal Information

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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