Potassium Organotrifluoroborates

Organotrifluoroborates: Versatile and Stable Boronic Acid Surrogates

Prof. Gary Molander has extensively developed the chemistry of organotrifluoroborates. These bench stable boronic acid surrogates are useful for Suzuki-Miyaura cross-coupling reactions and have also been used for a variety of other C-C bond forming reactions. Importantly, these reagents are compatible with a wide range of functional groups and are stable to many commonly used and harsh reaction conditions.

 

Benefits of Organtrifluoroborates:

• Bench stable reagents that can be stored indefinitely
• Can be effectively coupled with a wide range of organic electrophiles
• Exist as tetracoordinated monomeric species
• Are less prone to protodeboronation than their boronic acid or boronate ester counterparts

Suzuki-Miyaura Cross-Coupling with Organotrifluoroborates

Organotrifluoroborates from us

For a complete list of organotrifluoroborates.

1. Molander G, Figueroa R. 2005. Aldrichimica Acta.(38):49-56.

2. Darses S, Genet J. 2003. Potassium Trifluoro(organo)borates: New Perspectives in Organic Chemistry. Eur. J. Org. Chem.. 2003(22):4313-4327. https://doi.org/10.1002/ejoc.200300294