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  • Genetic editing of the androgen receptor contributes to impaired male courtship behavior in zebrafish.

Genetic editing of the androgen receptor contributes to impaired male courtship behavior in zebrafish.

The Journal of experimental biology (2017-06-18)
Lengxob Yong, Zayer Thet, Yong Zhu
초록

Elucidating the genes that contribute to behavioral variation has become an important endeavor in behavioral studies. While advances in genomics have narrowed down the list of candidate genes, functional validation of them has lagged behind, partly because of challenges associated with rapid gene manipulations. Consequently, few studies have demonstrated causal genetic changes linked to behaviors. The 'gene editing revolution' has offered unprecedented opportunities to investigate candidate genes responsible for critical behaviors. Here, we edited the androgen receptor gene (

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Sigma-Aldrich
Phenol red solution, 0.5%, liquid, sterile-filtered, BioReagent, suitable for cell culture