- Demethylation of 2,4-dimethoxyquinolines: the synthesis of atanine.
Demethylation of 2,4-dimethoxyquinolines: the synthesis of atanine.
Organic & biomolecular chemistry (2003-12-20)
Keith Jones, Xavier Roset, Sharon Rossiter, Philip Whitfield
PMID14685309
초록
The synthesis of the quinoline alkaloid atanine 6, by selective demethylation of the 2,4-dimethoxyquinoline 11 is presented. An alternative demethylation utilising a thiolate anion leads to the regioisomeric 4-hydroxyquinoline 13.