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Merck
  • Direct synthesis of tricyclic 5H-pyrido[3,2,1-ij]quinolin-3-one by domino palladium catalyzed reaction.

Direct synthesis of tricyclic 5H-pyrido[3,2,1-ij]quinolin-3-one by domino palladium catalyzed reaction.

Organic & biomolecular chemistry (2006-10-07)
Sébastien Noël, Catherine Pinel, Laurent Djakovitch
초록

Unexpectedly, the palladium catalyzed coupling reaction of acrolein with 8-bromoquinoline gave 5H-pyrido[3,2,1-ij]quinolin-3-one in a single step.