Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.

Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.

Journal of inorganic biochemistry (2012-07-24)

A G Quiroga

PMID22819649

초록

This focused review is devoted to our advances in developing trans platinum complexes as antitumoral complexes, in particular those bearing aliphatic amines. It includes some fundamental aspects of the understanding of non conventional metallodrug mechanism. The perspective is arranged by those fundamental aspects and within each section only the most successful examples have been included and also those in which clearly SAR's (structure activity relationships) have been observed.

MATERIALS

제품 번호

브랜드

제품 설명

349402

Sigma-Aldrich

Platinum, wire, diam. 0.25 mm, 99.9% trace metals basis

349348

Sigma-Aldrich

Platinum, foil, thickness 0.127 mm, 99.99% trace metals basis

444685

Sigma-Aldrich

Platinum, wire, diam. 2.0 mm, 99.9% trace metals basis

349321

Sigma-Aldrich

Platinum, foil, thickness 0.25 mm, 99.99% trace metals basis

327484

Sigma-Aldrich

Platinum, shot, ≤3 mm, ≥99.9% trace metals basis

520780

Sigma-Aldrich

Platinum black, ≥99.9% trace metals basis

298093

Sigma-Aldrich

Platinum, gauze, 100 mesh, 99.9% trace metals basis

267821

Sigma-Aldrich

Platinum, wire, diam. 0.127 mm, 99.9% trace metals basis

520799

Sigma-Aldrich

Platinum black, low bulk density, ≥99.9% trace metals basis

349380

Sigma-Aldrich

Platinum, foil, thickness 0.1 mm, 99.9% trace metals basis

205915

Sigma-Aldrich

Platinum black, black, powder, ≤20 μm, ≥99.95% trace metals basis

357375

Sigma-Aldrich

Platinum, wire, diam. 0.076 mm, ≥99.99% trace metals basis

267244

Sigma-Aldrich

Platinum, foil, thickness 0.025 mm, 99.9% trace metals basis

GF58265488

Platinum, foil, not light tested, 50x50mm, thickness 0.004mm, as rolled, 99.95%

GF57762399

Platinum, foil, not light tested, 50x50mm, thickness 0.005mm, as rolled, 99.95%

GF40155533

Platinum, foil, light tested, 25x25mm, thickness 0.005mm, as rolled, 99.95%

GF95421450

Platinum, foil, not light tested, 100x100mm, thickness 0.01mm, as rolled, 99.95%

GF84594897

Platinum, wire reel, 0.5m, diameter 0.125mm, as drawn, 99.95%

GF02102948

Platinum, foil, light tested, 25x25mm, thickness 0.025mm, as rolled, 99.99+%

GF00716149

Platinum, wire reel, 2m, diameter 0.3mm, as drawn, may be used as one component of a thermocouple, 99.99%

GF95238939

Platinum, wire reel, 2m, diameter 0.125mm, as drawn, 99.95%

GF43583283

Platinum, wire reel, 1m, diameter 0.04mm, annealed, may be used as one component of a thermocouple, 99.99%

GF12344677

Platinum, foil, not light tested, 50x50mm, thickness 0.0015mm, as rolled, 99.95%

GF14090644

Platinum, wire reel, 1m, diameter 0.20mm, annealed, may be used as one component of a thermocouple, 99.99%

GF35942632

Platinum, wire reel, 2m, diameter 0.15mm, annealed, may be used as one component of a thermocouple, 99.99%

GF16313723

Platinum, wire reel, 1m, diameter 0.002mm, wollaston, 99.9%

GF39448873

Platinum, foil, light tested, 50x50mm, thickness 0.005mm, as rolled, 99.95%

GF76686924

Platinum, wire reel, 10m, diameter 0.08mm, hard, 99.9%

GF95233710

Platinum, wire reel, 2m, diameter 0.25mm, hard, 99.95%

GF33625683

Platinum, wire, straight, 200mm, diameter 0.1mm, hard, 99.99%