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  • Steric parameters in the Ir-catalyzed regio- and diastereoselective isomerization of primary allylic alcohols.

Steric parameters in the Ir-catalyzed regio- and diastereoselective isomerization of primary allylic alcohols.

Organic letters (2013-11-14)
Houhua Li, Clément Mazet
초록

The iridium-catalyzed diastereo- and regioselective isomerization of primary allylic alcohols using Crabtree's catalyst or sterically modified analogs is reported. The importance of the size of the substituents on either the substrates or the catalysts has been rationalized by linear free energy relationships.

MATERIALS
제품 번호
브랜드
제품 설명

Sigma-Aldrich
Iridium, powder, 99.9% trace metals basis
Sigma-Aldrich
Allyl alcohol, ≥99%
Sigma-Aldrich
Iridium, foil, thickness 0.25 mm, 99.9% trace metals basis
Sigma-Aldrich
Iridium, evaporation slug, diam. × L 0.6 cm × 1.2 cm, 99.9% trace metals basis
Sigma-Aldrich
Allyl alcohol, ≥98.5%