콘텐츠로 건너뛰기
Merck
  • Development of a tailor-made bis(oxazolidine)pyridine-metal catalyst for the [3+2] cycloaddition of azomethine imines with propiolates.

Development of a tailor-made bis(oxazolidine)pyridine-metal catalyst for the [3+2] cycloaddition of azomethine imines with propiolates.

Chemical communications (Cambridge, England) (2013-08-01)
Takayoshi Arai, Yuta Ogino, Toru Sato
초록

A series of bis(oxazolidine)pyridine ligands (the PyBodines) were newly designed and synthesized for the development of a highly efficient, tailor-made catalyst for the [3+2] cycloaddition of azomethine imines with propiolates. The PyBodine(l-Ala)-Cu(OAc)2 catalyst was selected on the basis of solid-phase catalysis/CD-HTS and exhibited high efficiency, producing the (R)-adducts with excellent enantioselectivity.

MATERIALS
제품 번호
브랜드
제품 설명

Sigma-Aldrich
Pyridine hydrochloride, purum, ≥98.0% (AT)
Sigma-Aldrich
Pyridine hydrochloride, 98%
Supelco
Pyridine solution, certified reference material, 2000 μg/mL in methanol
Sigma-Aldrich
Pyridine, ≥99%
Sigma-Aldrich
Pyridine hydrobromide, 98%
Supelco
Pyridine, analytical standard
Sigma-Aldrich
Pyridine, anhydrous, 99.8%
Sigma-Aldrich
Propiolic acid, 95%
Sigma-Aldrich
Pyridine, suitable for HPLC, ≥99.9%
Sigma-Aldrich
Pyridine, ReagentPlus®, ≥99%
Sigma-Aldrich
Pyridine, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.5% (GC)
Sigma-Aldrich
Pyridine, biotech. grade, ≥99.9%
Sigma-Aldrich
Pyridine, ReagentPlus®, ≥99%
Sigma-Aldrich
Pyridine, ACS reagent, ≥99.0%