Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues.

Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues.

Chemical communications (Cambridge, England) (2006-05-31)

Steven J Moss, Isabelle Carletti, Carlos Olano, Rose M Sheridan, Michael Ward, Vidya Math, Mohammad Nur-E-Alam, Alfredo F Braña, Ming Qiang Zhang, Peter F Leadlay, Carmen Méndez, José A Salas, Barrie Wilkinson

PMID16733573

초록

We report the directed biosynthesis of borrelidin analogues and their selective anti-proliferative activity against human cancer cell lines.

MATERIALS

제품 번호

브랜드

제품 설명

B3061

Sigma-Aldrich

Borrelidin, from Streptomyces parvulus, ≥98% (HPLC)