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Merck
  • [An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors].

[An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors].

Radiobiologiia (1993-01-01)
V I Kulinskiĭ, V Z Gorkin, A D Klimova, N P Rumiantseva
초록

Specific 2-propynylamine inhibitors of monoamine oxidase (MAO) pargyline and especially chlorgyline, a selective inhibitor of MAO A (but not deprenyl, a selective inhibitor of MAO B) increase the radioprotective effect of small doses of O-methyltyramine and phenylephrine and do not change the efficacy of large doses. This is consistent with the receptor theory of the mechanism of protective action of amines.

MATERIALS
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Sigma-Aldrich
4-Methoxyphenethylamine, ≥98%