The synthesis of 2-deoxy-α-D-glycosides from D-glycals catalyzed by TMSI and PPh3.

2-Deoxyglycosides were synthesized in high α-selectivity by the direct addition of alcohols to D-glucal and D-galactal catalyzed by TMSI and PPh(3). The acid labile isopropylidene group is tolerated under this condition.