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Merck
  • Sclerotherapy in tumescent anesthesia of reticular veins and telangiectasias.

Sclerotherapy in tumescent anesthesia of reticular veins and telangiectasias.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (2012-01-25)
Albert-Adrien Ramelet
초록

Some leg telangiectasias may be refractory to treatment, including sclerotherapy and lasers. To describe the innovative Sclerotherapy in Tumescent Anesthesia of Reticular veins and Telangiectasias (START) approach to achieving good results in such patients, which also proves effective in treating reticular veins. Because compression enhances the rate of success of sclerotherapy of C1 veins (telangiectasias and reticular), Ringer solution (with or without lidocaine-epinephrine) was injected subcutaneously before, during, or immediately after sclerotherapy of therapy-refractory C1 veins. This tumescence ensures an intratissular compression of the injected vessels for at least 1 hour. In the last 6 years, we have treated more than 300 patients. Telangiectasias that had resisted several previous treatments faded or disappeared in the majority of the cases treated, but the rate of complications (pigmentation, necrosis of small areas, and tiny scars) was higher than with usual sclerotherapy. Developed after observing the good results achieved by perioperative sclerotherapy of telangiectasias during ambulatory phlebectomy, the START technique is an effective and economic treatment of therapy-resistant telangiectasias, although because the rate of complications is higher than with usual sclerotherapy of C1 veins, it should be performed only by experienced phlebologists and only on therapy-refractory vessels.

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Brij® L23 solution, 30 % (w/v) in H2O
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Decaethylene glycol mono­dodecyl ether, nonionic surfactant
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Thesit®, for membrane research
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ECO Brij® L23
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ECO BRIJ® L4, average Mn ~362
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Brij® L23, main component: tricosaethylene glycol dodecyl ether
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Brij® L23, suitable for Stein-Moore chromatography