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Merck

Towards preparative-scale, biocatalytic alkene reductions.

Chemical communications (Cambridge, England) (2010-10-06)
Despina J Bougioukou, Adam Z Walton, Jon D Stewart
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Simple strategies for using alkene reductase enzymes to produce gram-scale quantities of both (R)- and (S)-citronellal have been developed. The methodology is easily accessible to non-specialist laboratories, allowing alkene reductases to be added to the toolbox of routine synthetic transformations.

MATERIALS
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Supelco
(ยฑ)-Citronellal, analytical standard
Sigma-Aldrich
(ยฑ)-Citronellal, natural, ≥85%, FCC, FG
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(S)-(โˆ’)-Citronellal, 96%
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(ยฑ)-Citronellal, ≥95.0% (GC)
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(R)-(+)-Citronellal, technical grade