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Merck
  • Enabling olefin metathesis on proteins: chemical methods for installation of S-allyl cysteine.

Enabling olefin metathesis on proteins: chemical methods for installation of S-allyl cysteine.

Chemical communications (Cambridge, England) (2009-06-27)
Justin M Chalker, Yuya A Lin, Omar Boutureira, Benjamin G Davis
초록

Multiple, complementary methods are reported for the chemical conversion of cysteine to S-allyl cysteine on protein surfaces, a useful transformation for the exploration of olefin metathesis on proteins.

MATERIALS
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Sigma-Aldrich
Allyl chloride, ReagentPlus®, 99%
Sigma-Aldrich
Allyl chloride, reagent grade, 98%