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  • Studying the photoprotective activity of a new class of heteroaromatic antioxidants.

Studying the photoprotective activity of a new class of heteroaromatic antioxidants.

Bulletin of experimental biology and medicine (2009-06-11)
N L Sakina, A M Golubkov, L D Smirnov, M A Ostrovsky, A E Dontsov
초록

Photoprotective activity of heteroaromatic compounds (derivatives of 3-hydroxypyridine, amino-6-hydroxybenzothiazole, and 5-hydroxybenzimidazole) was studied in the system of UV-induced cardiolipin peroxidation. Although all three compounds had the antioxidant effect during free radical oxidation of luminol, only derivatives of amino-6-hydroxybenzothiazole and 5-hydroxybenzimidazole inhibited the process of UV-induced lipid peroxidation. The 3-hydroxypyridine derivative did not inhibit UV-induced cardiolipin peroxidation, which was probably related to degradation of this compound under the influence of UV light and formation of degradation products that cannot inhibit free radical processes.

MATERIALS
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브랜드
제품 설명

Sigma-Aldrich
3-Hydroxypyridine, 98%