SRP8030

Fn14 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• 동의어(들): CD266, E1A-associated protein p300, FGF-inducible 14, Tumor necrosis factor receptor superfamily member 12A
• UNSPSC 코드: 51111800
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in HEK 293 cells
• 분석: >95% (SDS-PAGE)
• 형태: lyophilized
• 분자량: ~35 kDa by SDS-PAGE
• 포장: pkg of 50 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: <0.1 EU/μg endotoxin, tested
• 색상: white
• UniProt 수납 번호: Q9NP84
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... TNFRSF12A(51330)

설명

일반 설명

TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.

물리적 형태

Lyophilized from PBS.

재구성

Reconstitute with 50 μL deionized water.

기타 정보

The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable