SRP6553

CIRBP/Cold-inducible RNA-binding protein human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 동의어(들): A18HNRNP, CIRP
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥90% (SDS-PAGE)
• 형태: lyophilized
• 분자량: 20.5 kDa
• 포장: pkg of 1 mg; pkg of 20 μg
• 불순물: ≤1 EU/μg endotoxin (LAL test)
• UniProt 수납 번호: Q14011
• 배송 상태: wet ice
• 저장 온도: −70°C
• 유전자 정보: human ... CIRBP(1153)

설명

일반 설명

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

물리적 형태

Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.

재구성

Detailed reconstitution instructions are sent along with the product

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H315,H319,H360D
• 예방조치 성명서: P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable