생물학적 소스
human
재조합
expressed in baculovirus infected Sf9 cells
분석
≥80% (SDS-PAGE)
양식
aqueous solution
분자량
125 kDa
포장
pkg of 20 μg
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−70°C
유전자 정보
human ... KDM5A(5927)
일반 설명
Human JARID1A, also known as KDM5A and RBBP2, (GenBank Accession No. NM_001042603), amino acids 1-1090 with C-terminal FLAG-tag, MW= 125 kDa, expressed in Sf9 cells via a Baculovirus expression system.
애플리케이션
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
Laura J C M van Zutven et al.
Genes, chromosomes & cancer, 45(5), 437-446 (2006-01-19)
Chromosome rearrangements are found in many acute leukemias. As a result, genes at the breakpoints can be disrupted, forming fusion genes. One of the genes involved in several chromosome aberrations in hematological malignancies is NUP98 (11p15). As NUP98 is close
Xue Zhou et al.
Cancer research, 70(10), 4214-4221 (2010-04-22)
Histone H3 lysine 4 (H3K4) trimethylation (H3K4me3) at the promoter region of genes has been linked to transcriptional activation. In the present study, we found that hypoxia (1% oxygen) increased H3K4me3 in both normal human bronchial epithelial Beas-2B cells and
Alexander Roesch et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(9), 1249-1257 (2005-04-02)
In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of retinoblastoma protein (pRb)-activity. Members of the previously described family of retinoblastoma-binding proteins (RBPs) are supposed to act as pRb-modulating factors. Based on
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