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Merck
모든 사진(1)

문서

SML2897

Sigma-Aldrich

Flomoxef Sodium

≥97% (HPLC)

동의어(들):

(6R,7R)-7-[[2-[(Difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monosodium salt, 6315-S Sodium salt, FMOX Sodium salt

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About This Item

실험식(Hill 표기법):
C15H17F2N6O7S2 · Na
CAS Number:
Molecular Weight:
518.45
UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

분석

≥97% (HPLC)

형태

powder

색상

white to beige

solubility

H2O: 2 mg/mL, clear

저장 온도

−20°C

생화학적/생리학적 작용

Flomoxef is a semisynthetic oxacephem antibiotic. Flomoxef exhibit activity against epidermides, streptococci, propionibacteria, and both methicillin-resistant and -susceptible Staphylococcus aureus. Flomoxef appear to be stable to the common plasmid beta-lactamases TEM and SH4V-1 or by the betalactamases of S. aureus or B. fragilis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Chen-Hsiang Lee et al.
Infection and drug resistance, 11, 2471-2480 (2018-12-21)
Flomoxef is potentially effective against β-lactamase-producing Enterobacteriaceae because limited clinical data demonstrate its effectiveness against Enterobacteriaceae bloodstream infections (BSIs) based on its minimum inhibitory concentrations (MICs). This study was conducted to determine the optimal breakpoints based on the survival of
Jen-Jia Yang et al.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 51(5), 681-687 (2017-07-12)
Suppression of intestinal flora by broad-spectrum antimicrobial agents facilitated risk of colonization or infection with resistant pathogen. We aimed to investigate the changes in bowel carriage of target resistant microorganisms (TRO) among patients treated with three different classes of Pseudomonas-sparing
H C Neu et al.
Antimicrobial agents and chemotherapy, 30(5), 638-644 (1986-11-01)
6315-S, a novel difluoromethyl thioacetamido oxacephem, had in vitro activity comparable to that of cefotaxime and moxalactam against Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Klebsiella oxytoca, Citrobacter diversus, Salmonella spp., and Shigella spp., inhibiting 90% at less than or equal

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