SML1616

ICA-069673

≥98% (HPLC)

• 동의어(들): ICA 069673, N-(2-Chloro-5-pyrimidinyl)-3,4-difluoro-benzamide
• 실험식(Hill 표기법): C₁₁H₆ClF₂N₃O
• CAS Number: 582323-16-8
• Molecular Weight: 269.63
• MDL number: MFCD20926351
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825502
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2
• InChI: 1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
• InChI key: IIBSHMFXVWTQSJ-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

ICA-069673 has higher selectivity towards KV7.2/KV7.3 heterodimeric channels than KV7.3/KV7.5 channels. ICA-069673 is considered as a part of gating modifiers.

ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener that is active in rodent epilepsy models.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3