SAB5701794

Anti-Phospho-Caveolin-1-Y14 antibody produced in rabbit

• UNSPSC 코드: 12352203
• NACRES: NA.43

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: liquid
• 종 반응성: mouse, human, rat
• 농도: 1.59 mg/mL
• 기술: western blot: 1:500-1:2000
• UniProt 수납 번호: Q03135
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pTyr14)
• 유전자 정보: human ... CAV1(857)

설명

일반 설명

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

면역원

A synthetic phosphorylated peptide around Y14 of human Caveolin-1 (NP_001744.2).

물리적 형태

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable