SAB5701760

Anti-Phospho-Lck-Y505 antibody produced in rabbit

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: liquid
• 종 반응성: mouse, rat, human
• 농도: 3.79 mg/mL
• 기술: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:1000
• UniProt 수납 번호: P06239
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pTyr505)
• 유전자 정보: human ... LCK(3932)

설명

일반 설명

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.

면역원

A synthetic phosphorylated peptide around Y505 of human Lck (NP_001036236.1).

물리적 형태

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable