SAB5700317

Anti-Phospho-MDM2-S166 antibody produced in rabbit

• 동의어(들): ACTFS, HDMX, MDM2, hdm2
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: 11-14; 24-55
• 종 반응성: rat, mouse, human
• 농도: 0.63 mg/ml
• 기술: immunofluorescence: 1:50-1:100; western blot: 1:500-1:1000
• UniProt 수납 번호: Q00987
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer166)
• 유전자 정보: human ... MDM2(4193)

설명

일반 설명

This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

면역원

A synthetic phosphorylated peptide around S166 of human MDM2 (NP_002383.2).

물리적 형태

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

저장 및 안정성

Store at -20℃. Avoid freeze / thaw cycles.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable