S3191

SKF-83565 hydrobromide

>98% (HPLC), solid

• 동의어(들): 6-chloro-1-(3-chlorophenyl)-7,8-dihydroxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
• 실험식(Hill 표기법): C₁₇H₁₇NO₂Cl₂ · HBr
• Molecular Weight: 419.14
• MDL number: MFCD04040025
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278703

속성

• 분석: >98% (HPLC)
• 형태: solid
• 색상: white
• solubility: DMSO: soluble 26 mg/mL; H₂O: soluble 4.5 mg/mL
• SMILES string: Br[H].CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c3cccc(Cl)c3
• InChI: 1S/C17H17Cl2NO2.BrH/c1-20-6-5-12-13(8-15(21)17(22)16(12)19)14(9-20)10-3-2-4-11(18)7-10;/h2-4,7-8,14,21-22H,5-6,9H2,1H3;1H
• InChI key: QEWVKGGLZQAOKJ-UHFFFAOYSA-N
• 유전자 정보: human ... DRD1(1812)

설명

애플리케이션

SKF-83565 hydrobromide may be used in dopaminergic cell signaling studies.

생화학적/생리학적 작용

SKF-83565 is a benzazepine derivative that partially antagonizes dopamine D₁ receptor and stimulates adenylate cyclase with limited efficacy and modulates dopaminergic-mediated cell responses.

Atypical D₁ dopamine receptor agonist. Displays antagonist activity in vitro and agonist activity in vivo.