추천 제품
종 반응성
human
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 13 pg/mL
standard curve range: 12.29-3000 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... IL36G(56300)
일반 설명
The IL36G ELISA kit provides for the Quantitative measurement of IL-36 gamma in Cell Culture Supernatants, Plasma and Serum.
Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types.
Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
Members of interleukin (IL)-1 family of cytokines play a vital role in regulating immune responses to infectious challenges and sterile insults. IL-36 is implicated in mucosal immunity, such as lung anti-bacterial responses. Interleukin-36 γ (IL36G) participates in inflammation response and differentiation. Overexpression of IL36G has been observed in psoriasis patients. Thus, down regulation IL36G can be considered as an effective method to treat psoriasis.
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
IL-1 family cytokines in cardiovascular disease.
Pfeiler S, et al.
Cytokine (2017)
Participation of interleukin family 1 in the development of inflammatory reaction in the infectious process. 1. General characteristics of the interleukin family 1.
Abaturov AE, et al.
CHILDS HEALTH (2014)
IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and-negative bacterial pneumonia.
Kovach MA, et al.
Mucosal Immunology, 10(5), 1320-1320 (2017)
IL-36γ inhibits differentiation and induces inflammation of keratinocyte via Wnt signaling pathway in psoriasis.
Wang W, et al.
International Journal of Medical Sciences, 14(10), 1002-1002 (2017)
Jennifer Mildenberger et al.
Autophagy, 13(10), 1664-1678 (2017-08-19)
Inflammation is crucial in the defense against infections but must be tightly controlled to limit detrimental hyperactivation. Our diet influences inflammatory processes and omega-3 polyunsaturated fatty acids (n-3 PUFAs) have known anti-inflammatory effects. The balance of pro- and anti-inflammatory processes
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