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Merck
모든 사진(3)

문서

P2191

Sigma-Aldrich

Poly(D,L-lactide-co-glycolide)

lactide:glycolide (50:50), mol wt 30,000-60,000

동의어(들):

LACTEL® B6010-2, PLGA

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About This Item

Linear Formula:
[C3H4O2]x[C2H2O2]y
MDL number:
UNSPSC 코드:
12352211
PubChem Substance ID:
NACRES:
NA.25

피드(feed) 비율

lactide:glycolide (50:50)

분자량

30,000-60,000

저장 온도

−20°C

SMILES string

OCC(O)=O.CC(O)C(O)=O

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일반 설명

Poly(D,L-lactide-co-glycolide) is a biodegradable and biocompatible polymer, which is used for drug delivery. It is used to treat rheumatoid arthritis, ulcerative colitis, Crohn′s disease, inflammatory lung diseases and ophthalmic inflammatory disorders. Poly(D,L-lactide-co-glycolide) functions as a potential cancer therapeutic target.

애플리케이션

Poly(D,L-lactide-co-glycolide) has been used to raise and sustain an increased lactate monomer level in the gel at a concentration relevant to dermal wounds.

특징 및 장점

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

물리적 형태

Biocompatible, biodegradable polymer.

법적 정보

Lactel is a registered trademark of Evonik Corp

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Characterization of biodegradable poly (D, L-lactide-co-glycolide) polymers and microspheres
Hausberger AG and DeLuca PP
Journal of Pharmaceutical and Biomedical Analysis, 13(6), 747-760 (1995)
PLGA-based nanoparticles: an overview of biomedical applications
Danhier F, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 161(2), 505-522 (2012)
Habibun Nabi et al.
Parasitology research, 116(1), 359-370 (2016-10-28)
Toxoplasmosis is one of the most common zoonotic protozoal diseases. Recent advances in biotechnology have produced recombinant protein, which are immunogenic, and progress in nano-pharmaceutics has generated encapsulated protein in nanospheres, which are suitable for vaccine delivery. DNA was extracted
Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms
Hunt TK, et al.
Antioxidants & Redox Signaling, 9(8), 1115-1124 (2007)
Ahmed A Abd-Rabou et al.
Biological trace element research, 193(2), 377-389 (2019-05-09)
Colon cancer in men and breast cancer in women are regarded as major health burdens, accounting for majority of cancer diagnoses globally. Doxorubicin (DOX) resistance in breast and colon cancers represents the main reason of unsuccessful therapy. The rationale of

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