P183
(+)-PD 128,907 hydrochloride
>97%, solid
동의어(들):
(+)-(4aR,10bR)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C14H19NO3 · HCl
CAS Number:
Molecular Weight:
285.77
MDL number:
UNSPSC 코드:
12352202
PubChem Substance ID:
NACRES:
NA.77
추천 제품
![GAL4 [(1-147) - AH] from Saccharomyces cerevisiae recombinant, expressed in E. coli, ≥80% (SDS-PAGE)](/deepweb/assets/sigmaaldrich/product/images/174/140/27ccc70c-c146-4db8-888e-496728638bd2/640/27ccc70c-c146-4db8-888e-496728638bd2.jpg)
분석
>97%
양식
solid
색상
off-white
solubility
ethanol: >10 mg/mL
DMSO: 18 mg/mL
H2O: 9 mg/mL
SMILES string
Cl.CCCN1CCO[C@H]2[C@H]1COc3ccc(O)cc23
InChI
1S/C14H19NO3.ClH/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15;/h3-4,8,12,14,16H,2,5-7,9H2,1H3;1H/t12-,14-;/m1./s1
InChI key
DCFXOTRONMKUJB-QMDUSEKHSA-N
유전자 정보
human ... DRD3(1814)
생화학적/생리학적 작용
Selective D3 dopamine receptor agonist.
주의사항
Light sensitive
법적 정보
Manufactured and sold with the permission of Warner-Lambert Company.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Assessment of cocaine-like discriminative stimulus effects of dopamine D3 receptor ligands.
Acri, et al.
European Journal of Pharmacology, 281 (1995)
F Sautel et al.
Neuroreport, 6(2), 329-332 (1995-01-26)
The functional potency of a series of dopamine agonists for increasing mitogenesis, measured by incorporation of [3H]thymidine, was established in transfected cell lines expressing human D2 or D3 receptors. The functional selectivity of agonists markedly differs from their binding selectivity.
H A DeWald et al.
Journal of medicinal chemistry, 33(1), 445-450 (1990-01-01)
The dopamine agonist profile of (+-)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano [4,3-b]-1,4-oxazin-9-ol (16a) and its enantiomers (16b-c) was examined. Racemic 16a exhibited moderate affinity for the dopamine (DA) D2 receptor labeled with the DA antagonist ligand [3H]haloperidol and moderate in vivo activity; it attenuated gamma-butyrolactone-stimulated
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
