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Merck
모든 사진(1)

문서

H8885

Sigma-Aldrich

Hydroxyzine dihydrochloride

≥97%

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C21H27ClN2O2 · 2HCl
CAS Number:
Molecular Weight:
447.83
EC Number:
MDL number:
UNSPSC 코드:
12161501
PubChem Substance ID:
NACRES:
NA.77

분석

≥97%

형태

powder

solubility

H2O: soluble
alcohol: soluble
chloroform: soluble

SMILES string

Cl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3

InChI

1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H

InChI key

ANOMHKZSQFYSBR-UHFFFAOYSA-N

유전자 정보

human ... HRH1(3269)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist.

애플리케이션

Hydroxyzine dihydrochloride has been used in the study of comparative anxiolytic activity of various drugs in experimental models of rats.

생화학적/생리학적 작용

Hydroxyzine dihydrochloride (HDH) is used to regulate anxiety. It is also used to treat bronchial asthma and to relax patients before surgery.

픽토그램

Health hazardExclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Slide 1 of 2

1 of 2

COMPARATIVE ANXIOLYTIC ACTIVITY OF VARIOUS DRUGS IN EXPERIMENTAL MODELS OF RATS
Vitthal K R, et al.
International Journal of Current Research and Review, 4(24), 77-77 (2012)
Acid-base titrimetric assay of hydroxyzine dihydrochloride in pharmaceutical samples
Rajendraprasad N, et al.
Chemical Industry Times / Hua Gong Shi Kan, 16(2), 127-132 (2010)
Sunita B Chhaiya et al.
Indian journal of dermatology, venereology and leprology, 78(5), 605-610 (2012-09-11)
Ivermectin has opened a new era in the management of scabies as orally effective drug. However, topical route has been little explored for ivermectin. To compare the efficacy and safety of topical permethrin, oral ivermectin, and topical ivermectin in the
Cristina Lopez-Peig et al.
BMC research notes, 5, 684-684 (2012-12-15)
Benzodiazepine (BZD), the long-term treatment of which is harmful for cognitive function, is widely prescribed by General Practitioners in Spain. Based on studies performed in other countries we designed a nurse-led BZD withdrawal program adapted to Spanish Primary Care working
Kaori Kimura-Kuroiwa et al.
Journal of anesthesia, 26(3), 422-428 (2012-02-22)
Investigation into the characteristics of anesthetic interactions may provide clues to anesthesia mechanisms. Dexmedetomidine, an α(2)-adrenergic receptor agonist, has become a popular sedative in intensive care, and hydroxyzine, a histamine receptor antagonist, is well known as a tranquilizing premedication for

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