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Merck
모든 사진(1)

문서

E6886

Sigma-Aldrich

5-Ethyluracil

동의어(들):

2,4-Dihydroxy-5-ethylpyrimidine, Homothymine

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About This Item

실험식(Hill 표기법):
C6H8N2O2
CAS Number:
Molecular Weight:
140.14
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:

mp

>300 °C (lit.)

SMILES string

CCC1=CNC(=O)NC1=O

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

V Thielking et al.
Biological chemistry, 378(5), 407-415 (1997-05-01)
Steady-state kinetics of the N6-adenine Dam methyltransferase have been measured using as substrates non-self-complementary tetradecanucleotide duplexes that contain the GATC target sequence. Modifications in the GATC target sequence of one or both of the strands included substitution of guanine by
Montserrat Terrazas et al.
Molecular diversity, 15(3), 677-686 (2010-11-17)
Oligoribonucleotides carrying 5-ethyluridine units were prepared using solid-phase phosphoramidite chemistry. The introduction of the tert-butyldimethylsilyl group at the 2'-OH position proceeded in good yield and very high 2'-regioselectivity. RNA duplexes carrying 5-ethyluridine either at the sense or the guide strands
J L Fischel et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 1(9), 991-996 (1995-09-01)
Dihydropyrimidine dehydrogenase (DPD) is the rate-limiting enzyme of 5-fluorouracil (FU) catabolism. Ethynyluracil (776C) is a very potent, mechanism-based irreversible DPD inhibitor that improves the antitumor efficacy and the therapeutic index of FU in laboratory animals. We tested the cytotoxic effects
S Marzabal et al.
Nucleic acids research, 23(18), 3648-3655 (1995-09-25)
We have measured steady-state kinetics of the N6-adenine methyltransferase Dam Mtase using as substrates non-selfcomplementary tetradecamer duplexs (d[GCCGGATCTAGACG]-d[CGTCTAGATCC-GGC]) containing the hemimethylated GATC target sequence in one or the other strand and modifications in the GATC target sequence of the complementary
T Hayakawa et al.
Nucleic acids research, 16(11), 4761-4776 (1988-06-10)
Decadeoxyribonucleotides containing uracil, 5-bromouracil, 5-cyanouracil and 5-ethyluracil in recognition sequences of restriction endonucleases Bgl II, Sau 3AI, Mbo I were synthesized. Decanucleotides containing 5-bromouracil in place of thymine had essentially the same susceptibility to all the restriction endonucleases. Uracil-containing decanucleotides

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