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Merck
모든 사진(1)

문서

D4036

Sigma-Aldrich

Dynorphin A Porcine Fragment 1-9

≥97% (HPLC)

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About This Item

실험식(Hill 표기법):
C52H84N18O11
CAS Number:
Molecular Weight:
1137.34
MDL number:
UNSPSC 코드:
12352200

분석

≥97% (HPLC)

UniProt 수납 번호

저장 온도

−20°C

SMILES string

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

Amino Acid Sequence

Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg

생화학적/생리학적 작용

Potent κ-agonist

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

L Miller et al.
European journal of pharmacology, 116(1-2), 159-163 (1985-10-08)
The inhibitory action of dynorphin-(1-9) on the electrically stimulated mouse vas deferens was seen to be antagonised by the delta-selective opioid antagonist ICI 174864. The observed delta-receptor mediated responses were partially, but not totally, prevented by peptidase inhibitors which protect
M G Gillan et al.
Journal of neurochemistry, 45(4), 1034-1042 (1985-10-01)
Following incubation of [3H]dynorphin A (1-8) and [3H]dynorphin A (1-9) with suspensions of guinea pig brain membranes, analysis of the supernatants by HPLC has shown that both peptides are degraded at 25 degrees C and at 0 degrees C. Bestatin
P Slater et al.
Neuropeptides, 8(1), 71-76 (1986-07-01)
The autoradiographic distribution of kappa opioid binding sites was evaluated in sections of monkey brain using the selective ligand [3H]dynorphin1-9. Kappa receptors were highly concentrated in the deep layers of the cerebral cortex, the substantia nigra, the hippocampus and the
X Wu et al.
Zhonghua fu chan ke za zhi, 30(12), 728-731 (1995-12-01)
To investigate the relationship between elevated luteinizing hormone (LH), hyperinsulinemia and neuropeptides in patients with polycystic ovarian syndrome (PCOS). An oral glucose (100g) tolerance test (OGTT) was performed in 15 normally menstruating women (control) and 30 PCOS women with LH/follicle
M Maruyama et al.
Brain research, 401(1), 14-22 (1987-01-13)
This paper describes the binding properties of [3H]peptidergic opioid ligands to binding sites solubilized from rat brain membranes by the treatment with 0.125% sodium glycodeoxycholate and 1 M NaCl. The highest amount of the specific binding of [3H]-[D-Ala2-, Met5]enkephalinamide was

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