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Merck
모든 사진(1)

문서

B8400

Sigma-Aldrich

Monoclonal Anti-Bovine IgG2 antibody produced in mouse

clone BG2-7, ascites fluid

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

mouse

결합

unconjugated

항체 형태

ascites fluid

항체 생산 유형

secondary antibodies

클론

BG2-7, monoclonal

포함

15 mM sodium azide

기술

capture ELISA: suitable
dot blot: suitable
indirect ELISA: 1:1,000
western blot: suitable

동형

IgG1

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

일반 설명

The IgG class antibodies contain two subclasses, IgG1 and IgG2, which have antigenic differences in the Fc portion of the heavy chains. Monoclonal Anti-Bovine IgG2 (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes of an immunized mouse.

면역원

Purified bovine IgG

애플리케이션

Monoclonal Anti-Bovine IgG2 antibody has been used in:
  • western blot
  • enzyme linked immunosorbent assay (ELISA)
  • dot blot assay

생화학적/생리학적 작용

Bovine IgGs are glycoprotein antibodies that regulate immune responses in herds. These antibodies inhibit TLR5 activation upon immunization with native H7 flagellin. Bovine IgG levels can be used for the detection of Johne′s disease and milk adulteration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Detection of Bovine IgG Isotypes in a PPA-ELISA for Johne's Disease Diagnosis in Infected Herds
Fernandez B, et al.
Veterinary Medicine International, 2012 (2012)
Measurement of bovine IgG by indirect competitive ELISA as a means of detecting milk adulteration
Hurley IP, et al.
Journal of Dairy Science, 87(3), 543-549 (2004)
Macarena Sarli et al.
PloS one, 15(2), e0229301-e0229301 (2020-02-23)
Anaplasma marginale is the most prevalent tick-borne livestock pathogen with worldwide distribution. Bovine anaplasmosis is a significant threat to cattle industry. Anaplasmosis outbreaks in endemic areas are prevented via vaccination with live A. centrale produced in splenectomized calves. Since A.
Tom N McNeilly et al.
Vaccine, 28(5), 1412-1421 (2009-11-21)
Systemic immunization of cattle with H7 flagellin results in induction of both H7-specific IgA and IgG antibodies but only partially protects against subsequent colonization with Escherichia coli O157:H7. Recent studies indicate that anti-flagellin antibodies directed against TLR5 binding domains located

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