05130

L-Alanine

≥99.0% (NT)

• 동의어(들): (S)-2-Aminopropionic acid, L-α-Aminopropionic acid
• 실험식(Hill 표기법): C₃H₇NO₂
• CAS Number: 56-41-7
• Molecular Weight: 89.09
• Beilstein: 1720248
• EC Number: 200-273-8
• MDL number: MFCD00064410
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 329747640
• NACRES: NA.26

속성

• 분석: ≥99.0% (NT)
• 형태: powder or crystals
• 광학 활성: [α]20/D +14.0±1°, c = 5% in 5 M HCl
• 불순물: ≤0.3% foreign amino acids
• 무기 잔류물: ≤0.1% (as SO₄)
• 손실: ≤0.1% loss on drying, 110 °C
• 색상: colorless to white
• mp: 314.5 °C
• solubility: H₂O: soluble 89.1 g/l at 20 degrees c; diethyl ether: insoluble; ethanol: soluble (cold 80%)
• 음이온 미량물: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• 양이온 미량물: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; NH₄⁺: ≤100 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• 응용 분야: detection; peptide synthesis
• SMILES string: C[C@H](N)C(O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
• InChI key: QNAYBMKLOCPYGJ-REOHCLBHSA-N

설명

애플리케이션

L-Alanine is used as a standard to determine absolute concentration of a protein within a mixture of other proteins measured with SI traceability.

생화학적/생리학적 작용

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.

L-alanine has the ability to promote the expression of ferritin and antioxidant stress proteins, heme oxygenase-1 (HO-1).

제조 메모

L-Alanine completely dissolves in water at a concentration of 89.1 g/l at 20°C to yield solution. It is also soluble in 80% ethanol and insoluble in ether.

기타 정보

Preparation of 2-chloropropionic acid; Reduction of derivatives to the aldehyde

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)