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Merck
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Key Documents

SCT046

Sigma-Aldrich

BioTracker CyP AP Live Cell Dye

Live cell imaging dye for alkaline phosphatase (AP) for cancer and stem cell applications.

동의어(들):

Live cell imaging probe

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About This Item

UNSPSC 코드:
12352207
NACRES:
NA.47

분석

≥98% (H-NMR)
≥98% (HPLC)
≥98% (LC/MS)
≥98% (elemental analysis)

기술

cell based assay: suitable

검출 방법

fluorometric

배송 상태

ambient

일반 설명

Alkaline Phosphatase (AP) catalyzes the hydrolysis of the phosphate group in alkaline media. AP is an essential enzyme and widely distributes in a variety of tissues such as liver, intestine, kidney, bone, and placenta. Abnormal AP levels have been shown in numerous cancers, bone disease and liver dysfunction. AP is also expressed by pluripotent stem cells such as ES and IPS cells.

The BioTracker CyP AP dye is a live cell near-infrared (NIR) fluorescent imaging probe for alkaline phosphatase. With its long emission wavelength, the probe is suitable for monitoring AP levels in both in vivo and in vitro tissues and cells. The probe possesses deep tissue penetration, less damage to the biological samples, and lower interference from the background fluorescence compared to other AP probes.

Spectral Properties
Absorbance: 690nm
Emission: 738nm

애플리케이션

Live cell fluorescent imaging
Research Category
Cell Imaging
Research Sub Category
Live Cell Dye

품질

Purity: ≥ 98% confirmed by HNMR, LC-MS and HPLC and elemental analysis
Molar Mass: 528.55 g/mol

물리적 형태

Lyophilized

저장 및 안정성

Store BioTracker CyP AP Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Song-Jiao Li et al.
Analytical chemistry, 89(12), 6854-6860 (2017-05-19)
Alkaline phosphatase (ALP) is an essential enzyme and widely distributes in a variety of tissues. To date, various nanomaterial and small-molecule fluorescent probes for ALP have been constructed successfully, but the emission wavelengths of these probes are in the ultraviolet

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