ABN73

Anti-Neutral amino acid transporter (ASCT2) Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Neutral amino acid transporter B(0), Baboon M7 virus receptor, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 기술: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI 수납 번호: NP_005619
• UniProt 수납 번호: Q15758
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SLC1A5(6510)

설명

일반 설명

Neutral amino acid transporter, also known as ASCT2, is an alternate of the ASC (alanine-, serine-, cysteine-) transport system and is highly expressed in rat astroglia-rich cultures while not highly expressed in rat neuron-rich cultures. ASCT2 is also thought to be important in the glutamine release from cells. ASCT2 has been implicated in the growth and survival of cancer cells, therefore making it a possible target for cancer therapy. ASCT2 is thought to be a crucial neuronal neutral amino acid transporter.

특이성

No homology found to mouse or rat. Other homologies: rhesus monkey (93% sequence homology).

This antibody recognizes Neutral amino acid transporter at the N-terminus.

면역원

Epitope: N-terminus

KLH-conjugated linear peptide corresponding to the N-terminus of Neutral amino acid transporter.

애플리케이션

Anti-Neutral amino acid transporter (ASCT2) Antibody detects level of Neutral amino acid transporter (ASCT2) & has been published & validated for use in WB, IH(P).

Immunohistochemistry Analysis: 1:1000 dilution from a previous lot detected Neutral amino acid transporter in human prostate tissue.

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

품질

Evaluated by Western Blot in human placenta tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Neutral amino acid transporter on 10 µg of human placenta tissue lysate.

표적 설명

~ 57 kDa observed

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human placenta tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable