추천 제품
분석
>99% (TLC)
형태
powder
포장
pkg of 1 × 1 mg (700133P-1mg)
제조업체/상표
Avanti Research™ - A Croda Brand 700133P
배송 상태
dry ice
저장 온도
−20°C
SMILES string
O[C@H](C1)CC[C@](C1=C[C@H]2O)(C)C3C2C(CC[C@@H]4[C@H](C)CCCC(C)(O)CO)[C@]4(C)CC3
일반 설명
3β,25-OH-7-oxo-5-cholestenoic acid is a cholesterol derivative and an oxysterol derived from cholesterol. The synthesis of CA occurs in mitochondria and the enzyme sterol 27-hydroxylase (CYP27A1) catalyzes the step.
생화학적/생리학적 작용
Cholestenoic acid (CA) serves as a ligand to nuclear receptor and may be neurotoxic or neuroprotective based on their structural features. Defects in the enzymes catalyzing the formation of cholestenoic acids are implicated in disorders related to motor neuron degeneration.
포장
5 mL Amber Glass Screw Cap Vial (700133P-1mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Cholestenoic acid is a prognostic biomarker in acute respiratory distress syndrome.
The Journal of allergy and clinical immunology, 143(1), 440-442 (2018-10-09)
The Journal of clinical investigation, 124(11), 4829-4842 (2014-10-02)
Cholestenoic acids are formed as intermediates in metabolism of cholesterol to bile acids, and the biosynthetic enzymes that generate cholestenoic acids are expressed in the mammalian CNS. Here, we evaluated the cholestenoic acid profile of mammalian cerebrospinal fluid (CSF) and
The Journal of steroid biochemistry and molecular biology, 195, 105475-105475 (2019-09-22)
While the presence and abundance of the major oxysterols and cholestenoic acids in the circulation is well established, minor cholesterol metabolites may also have biological importance and be of value to investigate. In this study by observing the metabolism of
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