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Merck

TRPV4

transient receptor potential cation channel, subfamily V, member 4

동의어:
CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VRL2, VROAC
:
UniProtKB ID:
Clone ID:
  • Human(59341) Summary: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  • Mouse(63873) transient receptor potential cation channel, subfamily V, member 4
  • Rat(66026) transient receptor potential cation channel, subfamily V, member 4
  • naked mole-rat(101706710) transient receptor potential cation channel, subfamily V, member 4
  • domestic guinea pig(100724607) transient receptor potential cation channel, subfamily V, member 4
  • sheep(101113534) transient receptor potential cation channel, subfamily V, member 4
  • domestic cat(101084907) transient receptor potential cation channel, subfamily V, member 4
  • Horse(100066552) transient receptor potential cation channel, subfamily V, member 4
  • cow(540259) transient receptor potential cation channel, subfamily V, member 4
  • chicken(395427) transient receptor potential cation channel, subfamily V, member 4
  • dog(486308) transient receptor potential cation channel, subfamily V, member 4
  • Zebrafish(557850) transient receptor potential cation channel, subfamily V, member 4

Custom & Knockdown Gene Products

Small Molecule - Agonist

제품 번호
설명
Dihydrocapsaicin, from Capsicum sp., ≥85%,
rat, human
N-Vanillylnonanamide, ≥97%, powder,
rat

Small Molecule - Antagonist

제품 번호
설명
Capsazepine, ≥98% (HPLC), solid,
human, rat
Capsaicin, from Capsicum sp., ≥50% (HPLC),
rat, human
Capsaicin, natural,
rat, human
Capsaicin, ≥95%, from Capsicum sp.,
rat, human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
human, rat, mouse

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-TRPV4 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, rabbit
응용분야
immunohistochemistry
western blot
Anti-TRPV4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
종별 반응성
rat
응용분야
western blot
Anti-Transient Receptor Potential Vanilloid 4 Antibody, pain, Chemicon®, from rabbit,
종별 반응성
rat
응용분야
western blot
Anti-TRPV4 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot
Anti-TRPV4 Antibody, clone 1G10-L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
canine, human, mouse, rat
응용분야
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
Butamben, United States Pharmacopeia (USP) Reference Standard,
human
Capsaicin, from Capsicum sp., ≥50% (HPLC),
rat, human
Capsaicin, natural,
rat, human
Capsaicin, ≥95%, from Capsicum sp.,
rat, human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
human, rat, mouse

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
N-Vanillylnonanamide, ≥97%, powder,
rat
Capsazepine, ≥98% (HPLC), solid,
human, rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human TRPV4,
human
MISSION® esiRNA, targeting mouse Trpv4,
mouse