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Merck

TRPV1

transient receptor potential cation channel, subfamily V, member 1

동의어:
VR1
:
UniProtKB ID:
Clone ID:
  • Human(7442) Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(193034) transient receptor potential cation channel, subfamily V, member 1
  • Rat(83810) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(101093406) transient receptor potential cation channel, subfamily V, member 1
  • chicken(395259) transient receptor potential cation channel, subfamily V, member 1
  • naked mole-rat(101720480) transient receptor potential cation channel, subfamily V, member 1
  • Domestic Rabbit(100008926) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(100303454) transient receptor potential cation channel, subfamily V, member 1
  • Zebrafish(561195) transient receptor potential cation channel, subfamily V, member 1
  • cow(539074) transient receptor potential cation channel, subfamily V, member 1
  • domestic guinea pig(100135466) transient receptor potential cation channel, subfamily V, member 1
  • Horse(100034158) transient receptor potential cation channel, subfamily V, member 1
  • sheep(101110158) transient receptor potential cation channel, subfamily V, member 1
  • dog(445457) transient receptor potential cation channel, subfamily V, member 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

제품 번호
설명
Dihydrocapsaicin, from Capsicum sp., ≥85%,
rat, human
N-Vanillylnonanamide, ≥97%, powder,
rat
N-Oleoylethanolamine, ~98% (TLC),
human, mouse, rat

Small Molecule - Antagonist

제품 번호
설명
SB-366791, ≥98% (HPLC), powder,
human
Capsazepine, ≥98% (HPLC), solid,
human, rat
Capsaicin, from Capsicum sp., ≥50% (HPLC),
rat, human
Capsaicin, ≥95%, from Capsicum sp.,
rat, human
Capsaicin, natural,
rat, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-TRPV1 antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-Capsaicin Receptor Antibody, CT, serum, Chemicon®,
종별 반응성
rat
응용분야
immunohistochemistry
Anti-TRPV1 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
western blot
Anti-TRPV1 Antibody, clone 1N19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey, mouse
응용분야
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-TRPV1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot

Small Molecule - Inhibitor

제품 번호
설명
Olvanil, powder,
human
Paracetamol, British Pharmacopoeia (BP) Reference Standard,
human
Capsaicin, from Capsicum sp., ≥50% (HPLC),
rat, human
Capsaicin, ≥95%, from Capsicum sp.,
rat, human
Paracetamol, European Pharmacopoeia (EP) Reference Standard,
human

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
N-Vanillylnonanamide, ≥97%, powder,
rat
Capsazepine, ≥98% (HPLC), solid,
human, rat

Small Molecule - Opener

제품 번호
설명
Capsaicin, phyproof® Reference Substance,
human
Capsaicin, analytical standard,
human
Capsaicin, European Pharmacopoeia (EP) Reference Standard,
human
Capsaicin, United States Pharmacopeia (USP) Reference Standard,
human
Capsaicin, Pharmaceutical Secondary Standard; Certified Reference Material,
human

Proteins

제품 번호
설명
Capsaicin Receptor Control Peptide for AB5889, ,
rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human TRPV1,
human
MISSION® esiRNA, targeting mouse Trpv1,
mouse