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Merck

TNF

tumor necrosis factor

동의어:
DIF, TNF-alpha, TNFA, TNFSF2
종:
UniProtKB ID:
Clone ID:
  • Human(7124) Summary: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
  • Mouse(21926) tumor necrosis factor
  • Rat(24835) tumor necrosis factor
  • dog(403922) tumor necrosis factor
  • domestic cat(493755) tumor necrosis factor
  • Horse(100033834) tumor necrosis factor
  • Goat(100861232) tumor necrosis factor alpha
  • cow(280943) tumor necrosis factor
  • sheep(443540) tumor necrosis factor
  • Domestic Rabbit(100009088) tumor necrosis factor
  • domestic guinea pig(100135630) tumor necrosis factor
  • naked mole-rat(101718432) tumor necrosis factor

Custom & Knockdown Gene Products

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ELISA

제품 번호
설명
Rhesus Macaque TNFα / Tumor Necrosis Factor alpha ELISA Kit, ,

Small Molecule - Antagonist

제품 번호
설명
Abietic acid, technical, ~75% (GC),
human
Podocarpic acid, 98%,
human
SKF-86002, ≥98% (HPLC), solid,
human, rat
Forskolin, from Coleus forskohlii, ≥98% (HPLC), powder,
human
Myricetin, ≥96.0% (HPLC),
rat, mouse, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-TNFA antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry
Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse, clone 45418.111, purified immunoglobulin, lyophilized powder,
종별 반응성
rat
응용분야
ELISA
neutralization

western blot
Anti-Tumor Necrosis Factor-α antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
종별 반응성
human
응용분야
dot blot
microarray

neutralization
Monoclonal Anti-Tumor Necrosis Factor Receptor II antibody produced in mouse, clone 22221, purified immunoglobulin, lyophilized powder,
종별 반응성
human
응용분야
immunocytochemistry
microarray

neutralization
Anti-TNF-α antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
SKF-86002, ≥98% (HPLC), solid,
human, rat
SPD304, ≥98% (HPLC), solid,
mouse, rat, human
Myricetin, ≥96.0% (HPLC),
rat, mouse, human
Myricetin, ≥96.0%, crystalline,
rat, mouse, human
(−)-Thalidomide, >98%, solid,
human, mouse, rat

Proteins

제품 번호
설명
Tumor Necrosis Factor-α human, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
human
Tumor Necrosis Factor-α human, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
human
Tumor Necrosis Factor-α Protein, Recombinant human, Tumor Necrosis Factor-alpha (TNF-alpha) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells & certain other target cells.,
human
Tumor Necrosis Factor-α, human (hTNF-α), recombinant (yeast),
human
TNF-α human, Animal-component free, recombinant, expressed in E. coli, suitable for cell culture,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human TNF,
human
MISSION® esiRNA, targeting mouse Tnf,
mouse