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Merck

TNF

tumor necrosis factor

동의어:
DIF, TNF-alpha, TNFA, TNFSF2
:
UniProtKB ID:
Clone ID:
  • Human(7124) Summary: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
  • Mouse(21926) tumor necrosis factor
  • Rat(24835) tumor necrosis factor
  • dog(403922) tumor necrosis factor
  • domestic cat(493755) tumor necrosis factor
  • Horse(100033834) tumor necrosis factor
  • Goat(100861232) tumor necrosis factor alpha
  • cow(280943) tumor necrosis factor
  • sheep(443540) tumor necrosis factor
  • Domestic Rabbit(100009088) tumor necrosis factor
  • domestic guinea pig(100135630) tumor necrosis factor
  • naked mole-rat(101718432) tumor necrosis factor

Custom & Knockdown Gene Products

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ELISA

제품 번호
설명
Rhesus Macaque TNFα / Tumor Necrosis Factor alpha ELISA Kit, ,

Small Molecule - Antagonist

제품 번호
설명
Podocarpic acid, 98%,
human
Abietic acid, technical, ~75% (GC),
human
SKF-86002, ≥98% (HPLC), solid,
human, rat
Forskolin, from Coleus forskohlii, ≥98% (HPLC), powder,
human
(−)-Thalidomide, >98%, solid,
human, mouse, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-TNF antibody produced in mouse, clone 1C3-A1-F4, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-Tumor Necrosis Factor-α antibody produced in goat, affinity isolated antibody, lyophilized powder,
종별 반응성
mouse
응용분야
ELISA
flow cytometry

immunofluorescence

neutralization

western blot
Monoclonal Anti-Tumor Necrosis Factor-α–Fluorescein antibody produced in mouse, clone 6402.31, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
flow cytometry
Anti-Tumor Necrosis Factor-α antibody produced in goat, affinity isolated antibody, lyophilized powder,
종별 반응성
human
응용분야
immunohistochemistry
neutralization

western blot
Anti-Tumor Necrosis Factor-α Antibody, clone 195, clone 195, Chemicon®, from mouse,
종별 반응성
human
응용분야
immunocytochemistry
immunohistochemistry

neutralization

western blot

Small Molecule - Inhibitor

제품 번호
설명
SPD304, ≥98% (HPLC), solid,
mouse, rat, human
SKF-86002, ≥98% (HPLC), solid,
human, rat
(−)-Thalidomide, >98%, solid,
human, mouse, rat
(+)-Thalidomide, ≥98% (HPLC), powder,
human, mouse, rat
Probucol, analytical standard,
human

Proteins

제품 번호
설명
TNF-α human, Animal-component free, recombinant, expressed in E. coli, suitable for cell culture,
human
TNFα, low endotoxin, His tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
human
Tumor Necrosis Factor-α from mouse, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
mouse
Tumor Necrosis Factor-α human, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
human
Tumor Necrosis Factor-α human, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human TNF,
human
MISSION® esiRNA, targeting mouse Tnf,
mouse