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Merck

TLR4

toll-like receptor 4

동의어:
ARMD10, CD284, TLR-4, TOLL
:
UniProtKB ID:
Clone ID:
  • Human(7099) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(21898) toll-like receptor 4
  • Rat(29260) toll-like receptor 4
  • naked mole-rat(101715916) toll-like receptor 4
  • dog(403417) toll-like receptor 4
  • cow(281536) toll-like receptor 4
  • Horse(100066890) toll-like receptor 4
  • Domestic Rabbit(100009497) toll-like receptor 4
  • sheep(554263) toll-like receptor 4
  • Goat(100860955) toll-like receptor 4
  • domestic guinea pig(100724803) toll-like receptor 4
  • domestic cat(493698) toll-like receptor 4
  • chicken(417241) toll-like receptor 4

Custom & Knockdown Gene Products

ELISA

제품 번호
설명
Human TLR-4 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-TLR4 Mouse mAb (1H7), liquid, clone 1H7, Calbiochem®,
종별 반응성
human
응용분야
Anti-TLR4 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
Monoclonal Anti-TLR4 antibody produced in mouse, clone 3B6, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunohistochemistry

western blot
Anti-TLR4 Antibody, clone 2N20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey
응용분야
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human TLR4,
human